Uzsanna Kallo, Filippo La Torre, Enrico Corazziari, Leonardo Lenisa, Angelo Stuto, Marco Frascio, Paola De Nardi, Maciej Kierzkiewicz, Adam Dziki, Tomasz Blicharski, Jacek J. migielski, Michal Walczak, Henryke Mekle, Marek Horynski, Piotr P. Walega, Joanna J. Pisk z Wapinska, Barbara Wozniak-Stolarska, Gl ia Lacima, M ica Perona, Eloy Espin Basany, Federico Sopena, Pere Clave, Lluis Mundet, Omar Ortega, Wilhelm Graf, Magnus V. Andersson, Marianne Starck, Ulf Gunnarsson, Karin Strig d, Steven Brown, Charles Maxwell-Armstrong, Rudra Maitra, Carolynne Vaizey and Anton Emmanuel. The authors also acknowledge the contributions of A. John Camm, Hans-Juergen Gruss and Jackie Turner (study statistician). Ellen Robertshaw of Niche Science and Technologies Ltd. offered healthcare writing assistance, which was paid for by Norgine Ltd.Int J Colorectal Dis (2016) 31:1205216 Compliance with ethical standards Guarantor from the article D. Walker accepts duty for the integrity of the work as a complete, from inception to published short article. Distinct author contributions All authors were involved in the overview and interpretation with the data from this study.PDGF-BB Protein Species All authors contributed to improvement from the manuscript, which includes important review, and approved the final version from the article, which includes the authorship list. Economic help This study was funded by Norgine. Information analyses have been performed by Jackie Turner of Premier Investigation Group Ltd and funded by Norgine Restricted. Writing assistance was offered by Dr. Ellen Robertshaw of Niche Science and Technology Ltd. (Richmond, UK) and funded by Norgine Restricted. D. Walker, R. Ng Kwet Shing, C. Pediconi and J. Pilot are personnel of Norgine Restricted. J. Scholefield was remunerated by Norgine for his perform as Chair of the Data Monitoring Committee. Competing interests S. Wexner discloses honoraria from Incontinence Devices, Inc., Medtronic, Mederi, and Salix, and stock options from Renew Health-related. L. D. Walker, R. Ng Kwet Shing, C. Pediconi and J. Pilot are personnel of Norgine Limited. J. Scholefield was remunerated by Norgine for his operate as Chair of the Information Monitoring Committee.GM-CSF Protein Synonyms L.PMID:23381601 Siproudhis, W. Graf as well as a. Emmanuel have practically nothing to disclose. 11.1215 Omar M, Alexander CE (2013) Drug therapy for faecal incontinence in adults. Cochrane Database Syst Rev. doi:ten.1002/ 14651858 Kammerer-Doak DN, Dominguez C, Harner K et al (1998) Surgical repair of fecal incontinence. Correlation of sonographic anal sphincter integrity with subjective remedy. J Reprod Med 43:57680 Pfeifer J (2004) Good quality of life following sphincteroplasty. Acta Chir Iugosl 51:735 Altomare DF, De Fazio M, Giuliani RT et al (2010) Sphincteroplasty for fecal incontinence in the era of sacral nerve modulation. Globe J Gastroenterol 16:5267271 Findlay JM, Yeung JM, Robinson R et al (2010) Peripheral neuromodulation by means of posterior tibial nerve stimulation – a prospective remedy for faecal incontinence Ann R Coll Surg Engl 92:38590 Van Koughnett JA, Wexner SD (2013) Existing management of fecal incontinence: picking amongst treatment options to optimize outcomes. World J Gastroenterol 19:9216230 Barker A, Hurley J (2014) Novel remedy possibilities for fecal incontinence. Clin Colon Rectal Surg 27:11620 Rao SS (2014) Present and emerging therapy possibilities for fecal incontinence. J Clin Gastroenterol 48:75264 Hull T (2007) Fecal Incontinence. Clin Colon Rectal Surg 20:11824 Cook TA, Brading AF, Mortensen NJ (2001) The pharmacology of your internal anal sphincter and.