Product Name :
SN-38 glucuronide
Synonym :
7-Ethyl-10-hydroxy-camptothecin-10-O-b-Dglucuronide(4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7] indolizino[1,2-b]quinolin-9-yl b-D-glucopyranosiduronic acid
Chemical Name :
CAS NO.:
121080-63-5
Molecular formula :
C28H28N2O11
Molecular Weight:
568.53 g/mol
Classification :
MedChemExpress Products > Carbohydrates > Monosaccharides > SN-38 glucuronide
Description:
SN-38 glucuronide is a metabolite of irinotecan that inhibits the growth of cancer cells by binding to the DNA polymerase, blocking the synthesis of DNA. SN-38 glucuronide has potent antitumor activity and high values for inhibiting tumor metastasis. It is mainly excreted in urine as a conjugate with glucuronic acid, which may be why urine samples are often used to measure its concentration. SN-38 glucuronide also interacts with other drugs, including chemical inhibitors and ATP-binding cassette transporters, which can affect its pharmacological properties.
Purity :
>98%
Specifications :
1 mg
Price.:
450
Price unit :
$
Inventory :
In stock
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