Name :
IL18BP (Human) Recombinant protein
Biological Activity :
Human IL18BP (O95998, 31 a.a. – 194 a.a) partial recombinant protein with hIgG-His tag at C-terminal expressed in Sf9 cells.
Tag :
Protein Accession No. :
O95998
Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=10068
Amino Acid Sequence :
ADPTPVSQTT TAATASVRST KDPCPSQPPV FPAAKQCPAL EVTWPEVEVP LNGTLSLSCV ACSRFPNFSI LYWLGNGSFI EHLPGRLWEG STSRERGSTG TQLCKALVLE QLTPALHSTN FSCVLVDPEQ VVQRHVVLAQ LWAGLRATLP PTQEALPSSH SSPQQQGLEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSRDE LTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK HHHHHH.
Molecular Weight :
44.9
Storage and Stability :
Store at 4°C for 2~4 week. For long term storage store at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Aliquot to avoid repeated freezing and thawing.
Host :
insect
Interspecies Antigen Sequence :
Preparation Method :
Insect cell (Sf9) expression system
Purification :
Quality Control Testing :
Storage Buffer :
In PBS, pH 7.4 and 10% glycerol
Applications :
SDS-PAGE，
Gene Name :
IL18BP
Gene Alias :
IL18BPa
Gene Description :
interleukin 18 binding protein
Gene Summary :
The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn’s disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations :
MC51L-53L-54L homolog gene product|OTTHUMP00000179141|OTTHUMP00000179143
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