Campylobacter jejuni Antigen BA139VS

Additional Information:
targetCampylobacter jejuni|species reactivityCampylobacter jejuni|applicationsELISA|assay typeIndirect & quantitative|available size1 mg|Campylobacter jejuni Antigen BA139VSkitResearch areaInfectious DiseaseStorageStore at -65C or lower. Avoid repeated freeze-thaw cycles. Sonicate before use. 10 years from date of manufacture (under recommended storage conditions).FormliquidAssociated productsCampylobacter jejuni Antigen (BA139VS)Campylobacter jejuni IgA Control Serum (BC139A)Campylobacter jejuni IgG Control Serum (BC139G)Campylobacter jejuni IgM Control Serum (BC139M)Campylobacter jejuni IgA ELISA Kit (ESR139A)Campylobacter jejuni IgG ELISA Kit (ESR139G)Campylobacter jejuni IgM ELISA Kit (ESR139M)target relevanceOrganismCampylobacter jejuniStructure and strainsCampylobacter jejuni is a species of pathogenic bacteria, one of the most common causes of food poisoning in Europe and in the US. The vast majority of cases occur as isolated events, not as part of recognized outbreaks. Active surveillance through the Foodborne Diseases Active Surveillance Network (FoodNet) indicates that about 20 cases are diagnosed each year for each 100,000 people in the US, while many more cases are undiagnosed or unreported; the CDC estimates a total of 1.5 million infections every year. The European Food Safety Authority reported 246,571 cases in 2018, and estimated approximately nine million cases of human campylobacteriosis per year in the European Union.DiseaseCampylobacter is a bacteria consisting of more than 20 species occuring worldwide. In particular, Campylobacter jejuni is associated with human diseases in industrialized countries. The main reservoirs of the are warmblooded domestic and wild animals. Human Campylobacteriosis is primarily a foodborne disease. Insufficiently heated, contaminated poultry and poultry products (eggs excluded) are the main sources of infection. A clinical manifestation of Campylobacter jejuni infections is acute enteritis which is accompanied by fever (38 – 40C), headache, myalgia, anthralgia and weariness. Normally infections are self limiting, but 5 to 10% of untreated patients develop relapses. Rare complications of infection are Guillain-Barre-Syndrome, an inflammatory disease of the peripheral nervous system, and reactive arthritis. Diagnosis Campylobacter jejuni infections are usually detected by pathogen isolations from stool and blood samples. IDetection and diagnosisCampylobacter jejuni infections are usually detected by pathogen isolations from stool and blood samples. In recent years, serological diagnosis of Campylobacter jejuni infections has developed into an important routine diagnostic procedure. To analyze the etiology of severe complications, such as reactive arthritis and GBS, reliable serological ELISA tests are required, since these diseases usually develop up to three weeks after Campylobacter jejuni infection. In such cases, stool culture testing is not suitable since isolation attempts are usually unsuccessful at this stage.|