Product Name :
Rabbit anti-NAT8L Polyclonal Antibody(N-Term)
Synonym :
N-acetylaspartate synthetase; NAA synthetase; 2.3.1.17; Camello-like protein 3; N-acetyltransferase 8-like protein; NAT8L; CML3
Host :
Rabbit
Species Reactivity:
Human, Mouse
Specificity :
This NAT8L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 59-93 amino acids from human NAT8L.
Predicted Reactivity:
Mouse, Rat
Applications :
WB~~1:2000
Immunogen:
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles
Research areas :
Metabolism;Signal Transduction
Background :
Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.
UniProt :
Q8N9F0
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Description Purified Rabbit Polyclonal Antibody (Pab) |Synonym N-acetylaspartate synthetase; NAA synthetase; 2.3.1.17; Camello-like protein 3; N-acetyltransferase 8-like protein; NAT8L; CML3 |Host Rabbit |Specificity This NAT8L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 59-93 amino acids from human NAT8L. |Species Reactivity Human, Mouse |Predicted Reactivity Mouse, Rat |Applications WB~~1:2000 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles |Research areas Metabolism;Signal Transduction |Target |Background Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake. |Cellular localization Cytoplasm. Membrane; Single- pass membrane protein. Microsome membrane; Single-pass membrane protein Mitochondrion membrane; Single-pass membrane protein. Rough endoplasmic reticulum membrane; Single-pass membrane protein. Note=Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment |UniProt Q8N9F0 |References |References Hillier L.W.,et al.Nature 434:724-731(2005).Brandenberger R.,et al.Nat. Biotechnol. 22:707-716(2004).Ota T.,et al.Nat. Genet. 36:40-45(2004).Popsueva A.E.,et al.Dev. Biol. 234:483-496(2001).Arun P.,et al.Neurochem. Int. 55:219-225(2009). |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-NAT8L Polyclonal Antibody(N-Term)
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
1383716-33-3 Purity 156715-37-6 Technical Information PMID:20301652 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
